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{{Infobox anatomy | Name = Salivary glands | Image = | Caption = Location of the three pairs of major salivary glands and their associated ducts. | System = [[Exocrine system]], [[Digestive system]] | Function = Production of [[saliva]], lubrication, initial [[digestion]], and tooth protection. }} ==Definition== '''Salivary glands''' are [[exocrine glands]] in the [[oral cavity]] that produce and secrete '''[[saliva]]'''. Saliva contains enzymes (like [[amylase]]) that begin the breakdown of carbohydrates, as well as mucus, electrolytes, and antimicrobial agents that maintain oral health. The salivary system is divided into two main groups: the three pairs of **major salivary glands** and hundreds of **minor salivary glands**. ==Major Salivary Glands== ===1. Parotid Gland=== The largest of the salivary glands, located bilaterally in the pre-auricular region (in front of the ears). * '''Secretory type''': Purely '''serous''' (watery) secretion. * '''Duct''': '''[[Parotid duct]]''' (Stensen's duct), which opens into the oral vestibule opposite the maxillary second molar. * '''Innervation''': Secretomotor supply from the '''[[Glossopharyngeal nerve]]''' (CN IX). * '''Clinical Note''': The '''[[facial nerve]]''' (CN VII) passes through the gland but does not innervate it. ===2. Submandibular Gland=== Located in the submandibular triangle, medial to the body of the [[mandible]]. * '''Secretory type''': Mixed, but predominantly '''serous'''. * '''Duct''': '''[[Submandibular duct]]''' (Wharton's duct), which opens at the sublingual caruncle at the base of the tongue. * '''Innervation''': Secretomotor supply from the '''[[Facial nerve]]''' (CN VII) via the chorda tympani. ===3. Sublingual Gland=== The smallest of the major glands, located in the floor of the mouth, superior to the mylohyoid muscle. * '''Secretory type''': Mixed, but predominantly '''mucous''' (thick). * '''Duct''': Multiple small ducts (ducts of Rivinus) and the major sublingual duct (Bartholin's duct). * '''Innervation''': Same as the submandibular gland (CN VII). ==Minor Salivary Glands== There are 600 to 1,000 minor salivary glands distributed throughout the [[oral mucosa]] (except the anterior hard palate and gingiva). They are primarily mucous-secreting and provide continuous lubrication. ==Microscopic Anatomy== The functional unit of a salivary gland is the '''[[salivon]]''', which consists of: * '''Acinus''': A cluster of cells that produce the primary secretion. * '''Intercalated duct''': Short duct leading from the acinus. * '''Striated duct''': Involved in the reabsorption of sodium and secretion of potassium, making saliva '''hypotonic'''. * '''Excretory duct''': The final path to the oral cavity. ==Clinical Significance== * '''[[Sialolithiasis]]''': The formation of "salivary stones," most common in Wharton's duct due to the upward flow and high calcium content of submandibular saliva. * '''[[Xerostomia]]''': The subjective feeling of dry mouth, often a side effect of medications or '''[[Sjogren's syndrome]]'''. * '''[[Mucocele]]''': A common lesion caused by the rupture of a minor salivary gland duct, leading to mucus extravasation into the tissue. * '''[[Pleomorphic Adenoma]]''': The most common benign tumor of the salivary glands, usually occurring in the parotid. ==See Also== * [[Saliva]] * [[Oral mucosa]] * [[Sialography]] * [[Mumps]] [[Category:Anatomy]] [[Category:Oral Biology]] [[Category:Oral Pathology]]
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